P11802 (CDK4)

Overview
Predicted structure (AF):
AF-P11802-F1-model_v4
Uniprot entry:
P11802
Gene:
CDK4
Protein length:
303 residues
Mutations found:
5756
Benign based on D2Deep prediction:
3605 out of 5756 mutations
Pathogenic based on D2Deep prediction:
2151 out of 5756 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 5756 mutations across 303 unique positions. There are 3605 benign and 2151 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 P 19 0 19 0.003 0.621 View mutations
27 H 19 0 19 0.008 0.674 View mutations
28 S 15 4 19 0.286 0.597 View mutations
29 G 0 19 19 0.930 0.476 View mutations
30 H 16 3 19 0.182 0.487 View mutations
31 F 7 12 19 0.538 0.440 View mutations
32 V 3 16 19 0.835 0.535 View mutations
33 A 0 19 19 1.000 0.587 View mutations
34 L 4 15 19 0.780 0.452 View mutations
35 K 0 19 19 0.978 0.390 View mutations
36 S 17 2 19 0.111 0.576 View mutations
37 V 14 5 19 0.237 0.466 View mutations
38 R 8 11 19 0.622 0.432 View mutations
39 V 8 11 19 0.538 0.432 View mutations
40 P 17 2 19 0.151 0.689 View mutations
41 N 18 1 19 0.060 0.873 View mutations
42 G 17 2 19 0.136 0.884 View mutations
43 G 8 11 19 0.533 0.423 View mutations
44 G 1 18 19 0.955 0.065 View mutations
45 G 0 19 19 0.991 0.013 View mutations
46 G 1 18 19 0.930 0.180 View mutations
47 G 0 19 19 0.996 0.253 View mutations
48 G 0 19 19 1.000 0.496 View mutations
49 L 3 16 19 0.872 0.391 View mutations
50 P 1 18 19 0.931 0.418 View mutations