P11802 (CDK4)

Overview
Predicted structure (AF):
AF-P11802-F1-model_v4
Uniprot entry:
P11802
Gene:
CDK4
Protein length:
303 residues
Mutations found:
5756
Benign based on D2Deep prediction:
3605 out of 5756 mutations
Pathogenic based on D2Deep prediction:
2151 out of 5756 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5756 mutations across 303 unique positions. There are 3605 benign and 2151 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 D 0 19 19 0.965 0.527 View mutations
77 V 9 10 19 0.525 0.503 View mutations
78 C 3 16 19 0.853 0.418 View mutations
79 A 15 4 19 0.274 0.475 View mutations
80 T 9 10 19 0.494 0.438 View mutations
81 S 18 1 19 0.116 0.578 View mutations
82 R 11 8 19 0.440 0.500 View mutations
83 T 19 0 19 0.016 0.630 View mutations
84 D 19 0 19 0.004 0.595 View mutations
85 R 19 0 19 0.062 0.562 View mutations
86 E 19 0 19 0.001 0.503 View mutations
87 I 18 1 19 0.052 0.534 View mutations
88 K 18 1 19 0.061 0.464 View mutations
89 V 19 0 19 0.002 0.491 View mutations
90 T 19 0 19 0.000 0.466 View mutations
91 L 8 11 19 0.547 0.527 View mutations
92 V 19 0 19 0.000 0.368 View mutations
93 F 6 13 19 0.722 0.554 View mutations
94 E 1 18 19 0.897 0.763 View mutations
95 H 0 19 19 0.968 0.659 View mutations
96 V 2 17 19 0.899 0.605 View mutations
97 D 19 0 19 0.072 0.334 View mutations
98 Q 19 0 19 0.014 0.404 View mutations
99 D 18 1 19 0.096 0.476 View mutations
100 L 4 15 19 0.734 0.625 View mutations