P11912 (P11912)

Overview
Predicted structure (AF):
AF-P11912-F1-model_v4
Uniprot entry:
P11912
Gene:
P11912
Protein length:
226 residues
Mutations found:
4293
Benign based on D2Deep prediction:
2752 out of 4293 mutations
Pathogenic based on D2Deep prediction:
1541 out of 4293 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4293 mutations across 226 unique positions. There are 2752 benign and 1541 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 17 1 18 0.137 0.516 View mutations
2 P 17 2 19 0.204 0.653 View mutations
3 G 5 14 19 0.707 0.341 View mutations
4 G 13 6 19 0.289 0.547 View mutations
5 P 19 0 19 0.005 0.838 View mutations
6 G 19 0 19 0.005 0.864 View mutations
7 V 19 0 19 0.000 0.772 View mutations
8 L 19 0 19 0.000 0.823 View mutations
9 Q 19 0 19 0.002 0.901 View mutations
10 A 19 0 19 0.041 0.872 View mutations
11 L 19 0 19 0.003 0.890 View mutations
12 P 18 1 19 0.051 0.836 View mutations
13 A 19 0 19 0.053 0.880 View mutations
14 T 17 2 19 0.110 0.801 View mutations
15 I 19 0 19 0.013 0.876 View mutations
16 F 18 1 19 0.092 0.852 View mutations
17 L 18 1 19 0.071 0.817 View mutations
18 L 17 2 19 0.159 0.799 View mutations
19 F 19 0 19 0.020 0.876 View mutations
20 L 19 0 19 0.001 0.850 View mutations
21 L 13 6 19 0.392 0.612 View mutations
22 S 19 0 19 0.006 0.846 View mutations
23 A 17 2 19 0.183 0.751 View mutations
24 V 18 1 19 0.114 0.743 View mutations
25 Y 18 1 19 0.046 0.807 View mutations