P11912 (P11912)

Overview
Predicted structure (AF):
AF-P11912-F1-model_v4
Uniprot entry:
P11912
Gene:
P11912
Protein length:
226 residues
Mutations found:
4293
Benign based on D2Deep prediction:
2752 out of 4293 mutations
Pathogenic based on D2Deep prediction:
1541 out of 4293 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 4293 mutations across 226 unique positions. There are 2752 benign and 1541 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 L 18 1 19 0.059 0.735 View mutations
27 G 19 0 19 0.003 0.762 View mutations
28 P 17 2 19 0.157 0.726 View mutations
29 G 14 5 19 0.290 0.628 View mutations
30 C 15 4 19 0.234 0.744 View mutations
31 Q 19 0 19 0.036 0.742 View mutations
32 A 19 0 19 0.012 0.752 View mutations
33 L 19 0 19 0.021 0.820 View mutations
34 W 19 0 19 0.002 0.883 View mutations
35 M 17 2 19 0.093 0.792 View mutations
36 H 19 0 19 0.004 0.909 View mutations
37 K 18 1 19 0.052 0.870 View mutations
38 V 12 7 19 0.425 0.543 View mutations
39 P 19 0 19 0.009 0.666 View mutations
40 A 18 1 19 0.079 0.566 View mutations
41 S 17 2 19 0.146 0.578 View mutations
42 L 19 0 19 0.038 0.549 View mutations
43 M 19 0 19 0.002 0.673 View mutations
44 V 8 11 19 0.580 0.431 View mutations
45 S 13 6 19 0.314 0.572 View mutations
46 L 18 1 19 0.112 0.662 View mutations
47 G 18 1 19 0.095 0.570 View mutations
48 E 13 6 19 0.289 0.523 View mutations
49 D 19 0 19 0.026 0.857 View mutations
50 A 9 10 19 0.533 0.452 View mutations