P11912 (P11912)

Overview
Predicted structure (AF):
AF-P11912-F1-model_v4
Uniprot entry:
P11912
Gene:
P11912
Protein length:
226 residues
Mutations found:
4293
Benign based on D2Deep prediction:
2752 out of 4293 mutations
Pathogenic based on D2Deep prediction:
1541 out of 4293 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4293 mutations across 226 unique positions. There are 2752 benign and 1541 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 H 17 2 19 0.159 0.779 View mutations
52 F 19 0 19 0.012 0.690 View mutations
53 Q 18 1 19 0.110 0.774 View mutations
54 C 19 0 19 0.055 0.800 View mutations
55 P 19 0 19 0.005 0.838 View mutations
56 H 19 0 19 0.010 0.944 View mutations
57 N 19 0 19 0.024 0.838 View mutations
58 S 19 0 19 0.001 0.938 View mutations
59 S 19 0 19 0.001 0.918 View mutations
60 N 19 0 19 0.004 0.970 View mutations
61 N 19 0 19 0.014 0.901 View mutations
62 A 18 1 19 0.072 0.856 View mutations
63 N 19 0 19 0.025 0.733 View mutations
64 V 18 1 19 0.097 0.682 View mutations
65 T 19 0 19 0.031 0.685 View mutations
66 W 4 15 19 0.648 0.285 View mutations
67 W 17 2 19 0.182 0.706 View mutations
68 R 16 3 19 0.234 0.686 View mutations
69 V 19 0 19 0.008 0.767 View mutations
70 L 19 0 19 0.005 0.778 View mutations
71 H 19 0 19 0.009 0.845 View mutations
72 G 18 1 19 0.100 0.737 View mutations
73 N 18 1 19 0.107 0.782 View mutations
74 Y 19 0 19 0.034 0.870 View mutations
75 T 19 0 19 0.045 0.816 View mutations