P11912 (P11912)

Overview
Predicted structure (AF):
AF-P11912-F1-model_v4
Uniprot entry:
P11912
Gene:
P11912
Protein length:
226 residues
Mutations found:
4293
Benign based on D2Deep prediction:
2752 out of 4293 mutations
Pathogenic based on D2Deep prediction:
1541 out of 4293 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4293 mutations across 226 unique positions. There are 2752 benign and 1541 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 W 19 0 19 0.027 0.871 View mutations
77 P 19 0 19 0.018 0.814 View mutations
78 P 12 7 19 0.348 0.598 View mutations
79 E 19 0 19 0.043 0.916 View mutations
80 F 19 0 19 0.024 0.903 View mutations
81 L 19 0 19 0.027 0.901 View mutations
82 G 19 0 19 0.027 0.935 View mutations
83 P 19 0 19 0.002 1.000 View mutations
84 G 19 0 19 0.024 0.995 View mutations
85 E 19 0 19 0.004 0.998 View mutations
86 D 19 0 19 0.000 0.961 View mutations
87 P 19 0 19 0.004 0.881 View mutations
88 N 19 0 19 0.086 0.945 View mutations
89 G 19 0 19 0.000 0.893 View mutations
90 T 19 0 19 0.004 0.869 View mutations
91 L 19 0 19 0.003 0.781 View mutations
92 I 19 0 19 0.007 0.921 View mutations
93 I 12 7 19 0.360 0.563 View mutations
94 Q 19 0 19 0.001 0.897 View mutations
95 N 7 12 19 0.554 0.381 View mutations
96 V 0 19 19 0.958 0.253 View mutations
97 N 1 18 19 0.919 0.253 View mutations
98 K 3 16 19 0.806 0.301 View mutations
99 S 1 18 19 0.883 0.290 View mutations
100 H 3 16 19 0.811 0.340 View mutations