P11912 (P11912)

Overview
Predicted structure (AF):
AF-P11912-F1-model_v4
Uniprot entry:
P11912
Gene:
P11912
Protein length:
226 residues
Mutations found:
4293
Benign based on D2Deep prediction:
2752 out of 4293 mutations
Pathogenic based on D2Deep prediction:
1541 out of 4293 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4293 mutations across 226 unique positions. There are 2752 benign and 1541 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
201 D 0 19 19 0.994 0.882 View mutations
202 I 1 18 19 0.916 0.947 View mutations
203 S 9 10 19 0.548 0.521 View mutations
204 R 15 4 19 0.267 0.362 View mutations
205 G 5 14 19 0.727 0.707 View mutations
206 L 2 17 19 0.910 0.824 View mutations
207 Q 0 19 19 0.993 0.610 View mutations
208 G 0 19 19 0.982 0.837 View mutations
209 T 1 18 19 0.941 0.825 View mutations
210 Y 0 19 19 0.997 0.675 View mutations
211 Q 0 19 19 0.941 0.586 View mutations
212 D 0 19 19 0.990 0.825 View mutations
213 V 0 19 19 0.939 0.844 View mutations
214 G 0 19 19 0.992 0.798 View mutations
215 S 1 18 19 0.947 0.721 View mutations
216 L 1 18 19 0.962 0.719 View mutations
217 N 6 13 19 0.669 0.535 View mutations
218 I 10 9 19 0.486 0.489 View mutations
219 G 14 5 19 0.289 0.375 View mutations
220 D 18 1 19 0.131 0.255 View mutations
221 V 19 0 19 0.000 0.201 View mutations
222 Q 19 0 19 0.016 0.426 View mutations
223 L 19 0 19 0.011 0.164 View mutations
224 E 19 0 19 0.001 0.282 View mutations
225 K 19 0 19 0.004 0.348 View mutations