P11912 (P11912)

Overview
Predicted structure (AF):
AF-P11912-F1-model_v4
Uniprot entry:
P11912
Gene:
P11912
Protein length:
226 residues
Mutations found:
4293
Benign based on D2Deep prediction:
2752 out of 4293 mutations
Pathogenic based on D2Deep prediction:
1541 out of 4293 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 4293 mutations across 226 unique positions. There are 2752 benign and 1541 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 I 3 16 19 0.813 0.591 View mutations
152 L 2 17 19 0.920 0.601 View mutations
153 L 4 15 19 0.772 0.585 View mutations
154 F 8 11 19 0.573 0.518 View mutations
155 C 0 19 19 0.965 0.649 View mutations
156 A 1 18 19 0.947 0.698 View mutations
157 V 8 11 19 0.534 0.536 View mutations
158 V 1 18 19 0.970 0.693 View mutations
159 P 0 19 19 1.000 0.772 View mutations
160 G 0 19 19 1.000 0.857 View mutations
161 T 2 17 19 0.918 0.753 View mutations
162 L 0 19 19 1.000 0.840 View mutations
163 L 0 19 19 1.000 0.872 View mutations
164 L 0 19 19 0.978 0.849 View mutations
165 F 0 19 19 0.959 0.780 View mutations
166 R 0 19 19 1.000 0.697 View mutations
167 K 2 17 19 0.907 0.641 View mutations
168 R 7 12 19 0.651 0.543 View mutations
169 W 8 11 19 0.587 0.510 View mutations
170 Q 8 11 19 0.528 0.500 View mutations
171 N 12 7 19 0.371 0.497 View mutations
172 E 18 1 19 0.045 0.480 View mutations
173 K 18 1 19 0.044 0.394 View mutations
174 L 19 0 19 0.000 0.399 View mutations
175 G 19 0 19 0.017 0.443 View mutations