P11912 (P11912)

Overview
Predicted structure (AF):
AF-P11912-F1-model_v4
Uniprot entry:
P11912
Gene:
P11912
Protein length:
226 residues
Mutations found:
4293
Benign based on D2Deep prediction:
2752 out of 4293 mutations
Pathogenic based on D2Deep prediction:
1541 out of 4293 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 4293 mutations across 226 unique positions. There are 2752 benign and 1541 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 L 19 0 19 0.000 0.512 View mutations
177 D 19 0 19 0.051 0.511 View mutations
178 A 19 0 19 0.002 0.542 View mutations
179 G 18 1 19 0.115 0.518 View mutations
180 D 10 9 19 0.432 0.422 View mutations
181 E 13 6 19 0.284 0.492 View mutations
182 Y 10 9 19 0.447 0.498 View mutations
183 E 12 7 19 0.407 0.480 View mutations
184 D 3 16 19 0.792 0.632 View mutations
185 E 7 12 19 0.628 0.554 View mutations
186 N 8 11 19 0.583 0.535 View mutations
187 L 4 15 19 0.736 0.664 View mutations
188 Y 0 19 19 1.000 0.701 View mutations
189 E 0 19 19 0.971 0.777 View mutations
190 G 0 19 19 0.996 0.882 View mutations
191 L 0 19 19 1.000 0.837 View mutations
192 N 0 19 19 0.958 0.764 View mutations
193 L 4 15 19 0.750 0.689 View mutations
194 D 1 18 19 0.948 0.750 View mutations
195 D 1 18 19 0.935 0.768 View mutations
196 C 0 19 19 0.973 0.783 View mutations
197 S 5 14 19 0.725 0.644 View mutations
198 M 2 17 19 0.861 0.795 View mutations
199 Y 0 19 19 1.000 0.758 View mutations
200 E 0 19 19 0.902 0.874 View mutations