P15976 (GATA1)

Overview
Predicted structure (AF):
AF-P15976-F1-model_v4
Uniprot entry:
P15976
Gene:
GATA1
Protein length:
413 residues
Mutations found:
7846
Benign based on D2Deep prediction:
3634 out of 7846 mutations
Pathogenic based on D2Deep prediction:
4212 out of 7846 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7846 mutations across 413 unique positions. There are 3634 benign and 4212 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
401 P 14 5 19 0.338 0.533 View mutations
402 T 10 9 19 0.410 0.481 View mutations
403 T 14 5 19 0.244 0.632 View mutations
404 S 10 9 19 0.482 0.480 View mutations
405 T 16 3 19 0.169 0.565 View mutations
406 T 14 5 19 0.198 0.505 View mutations
407 V 15 4 19 0.241 0.491 View mutations
408 V 8 11 19 0.640 0.433 View mutations
409 A 11 8 19 0.406 0.434 View mutations
410 P 10 9 19 0.408 0.500 View mutations
411 L 1 18 19 0.950 0.471 View mutations
412 S 0 19 19 0.996 0.459 View mutations
413 S 0 19 19 0.999 0.435 View mutations