P16401 (P16401)

Overview
Predicted structure (AF):
AF-P16401-F1-model_v4
Uniprot entry:
P16401
Gene:
P16401
Protein length:
226 residues
Mutations found:
4293
Benign based on D2Deep prediction:
2597 out of 4293 mutations
Pathogenic based on D2Deep prediction:
1696 out of 4293 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Table results: 4293 mutations across 226 unique positions. There are 2597 benign and 1696 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 A 18 1 19 0.091 0.858 View mutations
127 G 17 2 19 0.200 0.786 View mutations
128 A 6 13 19 0.653 0.347 View mutations
129 A 18 1 19 0.117 0.831 View mutations
130 K 10 9 19 0.504 0.512 View mutations
131 A 16 3 19 0.201 0.779 View mutations
132 K 14 5 19 0.371 0.675 View mutations
133 K 19 0 19 0.023 0.904 View mutations
134 P 17 2 19 0.083 0.813 View mutations
135 A 19 0 19 0.002 0.892 View mutations
136 G 19 0 19 0.102 0.870 View mutations
137 A 18 1 19 0.097 0.816 View mutations
138 T 19 0 19 0.026 0.929 View mutations
139 P 19 0 19 0.015 0.913 View mutations
140 K 16 3 19 0.265 0.816 View mutations
141 K 19 0 19 0.119 0.940 View mutations
142 A 19 0 19 0.001 0.962 View mutations
143 K 19 0 19 0.032 0.977 View mutations
144 K 19 0 19 0.010 0.965 View mutations
145 A 19 0 19 0.003 0.931 View mutations
146 A 19 0 19 0.001 0.929 View mutations
147 G 16 3 19 0.160 0.803 View mutations
148 A 19 0 19 0.004 0.908 View mutations
149 K 19 0 19 0.001 0.893 View mutations
150 K 19 0 19 0.000 0.901 View mutations