P16401 (P16401)

Overview
Predicted structure (AF):
AF-P16401-F1-model_v4
Uniprot entry:
P16401
Gene:
P16401
Protein length:
226 residues
Mutations found:
4293
Benign based on D2Deep prediction:
2597 out of 4293 mutations
Pathogenic based on D2Deep prediction:
1696 out of 4293 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Table results: 4293 mutations across 226 unique positions. There are 2597 benign and 1696 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 A 19 0 19 0.024 0.887 View mutations
152 V 13 6 19 0.353 0.600 View mutations
153 K 19 0 19 0.003 0.807 View mutations
154 K 18 1 19 0.091 0.792 View mutations
155 T 12 7 19 0.427 0.581 View mutations
156 P 19 0 19 0.020 0.779 View mutations
157 K 19 0 19 0.005 0.830 View mutations
158 K 11 8 19 0.375 0.552 View mutations
159 A 19 0 19 0.001 0.866 View mutations
160 K 19 0 19 0.019 0.850 View mutations
161 K 13 6 19 0.291 0.607 View mutations
162 P 15 4 19 0.208 0.685 View mutations
163 A 18 1 19 0.061 0.806 View mutations
164 A 18 1 19 0.115 0.810 View mutations
165 A 19 0 19 0.018 0.847 View mutations
166 G 18 1 19 0.129 0.842 View mutations
167 V 19 0 19 0.000 0.892 View mutations
168 K 11 8 19 0.401 0.549 View mutations
169 K 19 0 19 0.000 0.870 View mutations
170 V 19 0 19 0.000 0.892 View mutations
171 A 17 2 19 0.100 0.795 View mutations
172 K 19 0 19 0.000 0.873 View mutations
173 S 19 0 19 0.002 0.842 View mutations
174 P 19 0 19 0.000 0.854 View mutations
175 K 19 0 19 0.022 0.840 View mutations