P16401 (P16401)

Overview
Predicted structure (AF):
AF-P16401-F1-model_v4
Uniprot entry:
P16401
Gene:
P16401
Protein length:
226 residues
Mutations found:
4293
Benign based on D2Deep prediction:
2597 out of 4293 mutations
Pathogenic based on D2Deep prediction:
1696 out of 4293 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Table results: 4293 mutations across 226 unique positions. There are 2597 benign and 1696 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 K 19 0 19 0.003 0.871 View mutations
177 A 19 0 19 0.001 0.883 View mutations
178 K 19 0 19 0.000 0.908 View mutations
179 A 19 0 19 0.008 0.853 View mutations
180 A 19 0 19 0.071 0.845 View mutations
181 A 19 0 19 0.000 0.875 View mutations
182 K 19 0 19 0.015 0.867 View mutations
183 P 19 0 19 0.054 0.800 View mutations
184 K 19 0 19 0.047 0.857 View mutations
185 K 17 2 19 0.086 0.758 View mutations
186 A 19 0 19 0.011 0.790 View mutations
187 T 18 1 19 0.087 0.789 View mutations
188 K 17 2 19 0.178 0.712 View mutations
189 S 8 11 19 0.578 0.427 View mutations
190 P 13 6 19 0.336 0.558 View mutations
191 A 12 7 19 0.438 0.568 View mutations
192 K 6 13 19 0.650 0.357 View mutations
193 P 13 6 19 0.331 0.601 View mutations
194 K 7 12 19 0.596 0.382 View mutations
195 A 10 9 19 0.474 0.503 View mutations
196 V 10 9 19 0.442 0.498 View mutations
197 K 18 1 19 0.085 0.850 View mutations
198 P 4 15 19 0.740 0.267 View mutations
199 K 19 0 19 0.073 0.854 View mutations
200 A 6 13 19 0.653 0.353 View mutations