P16403 (H1-2)

Overview
Predicted structure (AF):
AF-P16403-F1-model_v4
Uniprot entry:
P16403
Gene:
H1-2
Protein length:
213 residues
Mutations found:
4046
Benign based on D2Deep prediction:
2539 out of 4046 mutations
Pathogenic based on D2Deep prediction:
1507 out of 4046 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4046 mutations across 213 unique positions. There are 2539 benign and 1507 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
201 K 18 1 19 0.100 0.779 View mutations
202 V 19 0 19 0.052 0.824 View mutations
203 V 19 0 19 0.003 0.800 View mutations
204 K 19 0 19 0.044 0.802 View mutations
205 P 14 5 19 0.265 0.605 View mutations
206 K 13 6 19 0.392 0.608 View mutations
207 K 14 5 19 0.239 0.641 View mutations
208 A 18 1 19 0.102 0.692 View mutations
209 A 19 0 19 0.036 0.705 View mutations
210 P 19 0 19 0.029 0.638 View mutations
211 K 11 8 19 0.405 0.490 View mutations
212 K 1 18 19 0.929 0.316 View mutations
213 K 0 19 19 0.989 0.328 View mutations