P16403 (H1-2)

Overview
Predicted structure (AF):
AF-P16403-F1-model_v4
Uniprot entry:
P16403
Gene:
H1-2
Protein length:
213 residues
Mutations found:
4046
Benign based on D2Deep prediction:
2539 out of 4046 mutations
Pathogenic based on D2Deep prediction:
1507 out of 4046 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4046 mutations across 213 unique positions. There are 2539 benign and 1507 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 A 18 1 19 0.050 0.860 View mutations
152 K 17 2 19 0.133 0.814 View mutations
153 K 19 0 19 0.012 0.906 View mutations
154 T 18 1 19 0.045 0.875 View mutations
155 P 15 4 19 0.237 0.720 View mutations
156 K 19 0 19 0.012 0.887 View mutations
157 K 19 0 19 0.002 0.893 View mutations
158 A 19 0 19 0.018 0.863 View mutations
159 K 19 0 19 0.023 0.859 View mutations
160 K 19 0 19 0.013 0.843 View mutations
161 P 17 2 19 0.129 0.752 View mutations
162 A 17 2 19 0.203 0.775 View mutations
163 A 17 2 19 0.176 0.777 View mutations
164 A 10 9 19 0.411 0.498 View mutations
165 T 19 0 19 0.004 0.883 View mutations
166 V 17 2 19 0.090 0.787 View mutations
167 T 19 0 19 0.000 0.869 View mutations
168 K 12 7 19 0.370 0.577 View mutations
169 K 19 0 19 0.034 0.849 View mutations
170 V 19 0 19 0.000 0.863 View mutations
171 A 17 2 19 0.152 0.761 View mutations
172 K 19 0 19 0.012 0.822 View mutations
173 S 19 0 19 0.008 0.851 View mutations
174 P 19 0 19 0.001 0.832 View mutations
175 K 19 0 19 0.015 0.855 View mutations