P16403 (H1-2)

Overview
Predicted structure (AF):
AF-P16403-F1-model_v4
Uniprot entry:
P16403
Gene:
H1-2
Protein length:
213 residues
Mutations found:
4046
Benign based on D2Deep prediction:
2539 out of 4046 mutations
Pathogenic based on D2Deep prediction:
1507 out of 4046 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4046 mutations across 213 unique positions. There are 2539 benign and 1507 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 8 10 18 0.594 0.505 View mutations
2 S 11 8 19 0.485 0.433 View mutations
3 E 0 19 19 0.999 0.533 View mutations
4 T 5 14 19 0.651 0.429 View mutations
5 A 14 5 19 0.269 0.456 View mutations
6 P 16 3 19 0.164 0.469 View mutations
7 A 19 0 19 0.003 0.668 View mutations
8 A 18 1 19 0.036 0.642 View mutations
9 P 18 1 19 0.112 0.649 View mutations
10 A 19 0 19 0.022 0.769 View mutations
11 A 19 0 19 0.002 0.817 View mutations
12 A 14 5 19 0.298 0.640 View mutations
13 P 19 0 19 0.010 0.855 View mutations
14 P 18 1 19 0.077 0.869 View mutations
15 A 19 0 19 0.002 0.936 View mutations
16 E 19 0 19 0.000 0.919 View mutations
17 K 19 0 19 0.005 0.950 View mutations
18 A 18 1 19 0.049 0.905 View mutations
19 P 18 1 19 0.079 0.907 View mutations
20 V 19 0 19 0.004 0.941 View mutations
21 K 12 7 19 0.367 0.606 View mutations
22 K 17 2 19 0.081 0.836 View mutations
23 K 17 2 19 0.212 0.833 View mutations
24 A 18 1 19 0.071 0.841 View mutations
25 A 19 0 19 0.055 0.883 View mutations