P16403 (H1-2)

Overview
Predicted structure (AF):
AF-P16403-F1-model_v4
Uniprot entry:
P16403
Gene:
H1-2
Protein length:
213 residues
Mutations found:
4046
Benign based on D2Deep prediction:
2539 out of 4046 mutations
Pathogenic based on D2Deep prediction:
1507 out of 4046 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4046 mutations across 213 unique positions. There are 2539 benign and 1507 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 K 18 1 19 0.031 0.837 View mutations
177 A 19 0 19 0.005 0.900 View mutations
178 K 19 0 19 0.000 0.862 View mutations
179 V 19 0 19 0.000 0.797 View mutations
180 A 19 0 19 0.022 0.829 View mutations
181 K 19 0 19 0.001 0.819 View mutations
182 P 18 1 19 0.057 0.635 View mutations
183 K 15 4 19 0.303 0.638 View mutations
184 K 10 9 19 0.515 0.482 View mutations
185 A 19 0 19 0.002 0.671 View mutations
186 A 19 0 19 0.004 0.713 View mutations
187 K 10 9 19 0.453 0.474 View mutations
188 S 19 0 19 0.066 0.647 View mutations
189 A 10 9 19 0.460 0.470 View mutations
190 A 18 1 19 0.068 0.633 View mutations
191 K 11 8 19 0.529 0.492 View mutations
192 A 17 2 19 0.107 0.623 View mutations
193 V 19 0 19 0.053 0.717 View mutations
194 K 13 6 19 0.317 0.571 View mutations
195 P 19 0 19 0.057 0.628 View mutations
196 K 19 0 19 0.001 0.764 View mutations
197 A 19 0 19 0.003 0.825 View mutations
198 A 19 0 19 0.046 0.813 View mutations
199 K 18 1 19 0.157 0.785 View mutations
200 P 9 10 19 0.526 0.460 View mutations