P16422 (EPCAM)

Overview
Predicted structure (AF):
AF-P16422-F1-model_v4
Uniprot entry:
P16422
Gene:
EPCAM
Protein length:
314 residues
Mutations found:
5965
Benign based on D2Deep prediction:
3951 out of 5965 mutations
Pathogenic based on D2Deep prediction:
2014 out of 5965 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 5965 mutations across 314 unique positions. There are 3951 benign and 2014 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
301 E 16 3 19 0.228 0.456 View mutations
302 I 16 3 19 0.164 0.411 View mutations
303 K 1 18 19 0.965 0.449 View mutations
304 E 4 15 19 0.761 0.533 View mutations
305 M 19 0 19 0.001 0.388 View mutations
306 G 18 1 19 0.077 0.380 View mutations
307 E 13 6 19 0.376 0.499 View mutations
308 M 19 0 19 0.001 0.543 View mutations
309 H 19 0 19 0.044 0.595 View mutations
310 R 18 1 19 0.088 0.529 View mutations
311 E 18 1 19 0.065 0.549 View mutations
312 L 19 0 19 0.001 0.663 View mutations
313 N 19 0 19 0.008 0.580 View mutations
314 A 17 2 19 0.119 0.505 View mutations