P16422 (EPCAM)

Overview
Predicted structure (AF):
AF-P16422-F1-model_v4
Uniprot entry:
P16422
Gene:
EPCAM
Protein length:
314 residues
Mutations found:
5965
Benign based on D2Deep prediction:
3951 out of 5965 mutations
Pathogenic based on D2Deep prediction:
2014 out of 5965 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 5965 mutations across 314 unique positions. There are 3951 benign and 2014 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
276 V 8 11 19 0.611 0.429 View mutations
277 I 9 10 19 0.553 0.447 View mutations
278 A 9 10 19 0.549 0.445 View mutations
279 V 8 11 19 0.566 0.430 View mutations
280 V 2 17 19 0.865 0.339 View mutations
281 A 1 18 19 0.951 0.351 View mutations
282 G 8 11 19 0.615 0.432 View mutations
283 I 8 11 19 0.612 0.432 View mutations
284 V 2 17 19 0.876 0.406 View mutations
285 V 2 17 19 0.821 0.405 View mutations
286 L 14 5 19 0.256 0.467 View mutations
287 V 11 8 19 0.442 0.451 View mutations
288 I 6 13 19 0.647 0.425 View mutations
289 S 11 8 19 0.430 0.470 View mutations
290 R 14 5 19 0.245 0.480 View mutations
291 K 1 18 19 0.922 0.386 View mutations
292 K 2 17 19 0.874 0.371 View mutations
293 R 19 0 19 0.001 0.565 View mutations
294 M 13 6 19 0.320 0.501 View mutations
295 A 19 0 19 0.002 0.426 View mutations
296 K 17 2 19 0.114 0.443 View mutations
297 Y 0 19 19 0.962 0.440 View mutations
298 E 12 7 19 0.405 0.415 View mutations
299 K 2 17 19 0.889 0.503 View mutations
300 A 3 16 19 0.798 0.535 View mutations