P16422 (EPCAM)

Overview
Predicted structure (AF):
AF-P16422-F1-model_v4
Uniprot entry:
P16422
Gene:
EPCAM
Protein length:
314 residues
Mutations found:
5965
Benign based on D2Deep prediction:
3951 out of 5965 mutations
Pathogenic based on D2Deep prediction:
2014 out of 5965 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5965 mutations across 314 unique positions. There are 3951 benign and 2014 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 18 0 18 0.037 0.692 View mutations
2 A 18 1 19 0.057 0.794 View mutations
3 P 17 2 19 0.120 0.750 View mutations
4 P 19 0 19 0.003 0.845 View mutations
5 Q 19 0 19 0.027 0.881 View mutations
6 V 19 0 19 0.018 0.844 View mutations
7 L 19 0 19 0.001 0.904 View mutations
8 A 19 0 19 0.037 0.897 View mutations
9 F 15 4 19 0.273 0.713 View mutations
10 G 19 0 19 0.005 0.866 View mutations
11 L 19 0 19 0.002 0.826 View mutations
12 L 18 1 19 0.113 0.769 View mutations
13 L 17 2 19 0.082 0.753 View mutations
14 A 18 1 19 0.028 0.834 View mutations
15 A 19 0 19 0.001 0.856 View mutations
16 A 19 0 19 0.001 0.886 View mutations
17 T 19 0 19 0.003 0.903 View mutations
18 A 19 0 19 0.007 0.913 View mutations
19 T 19 0 19 0.032 0.965 View mutations
20 F 19 0 19 0.025 1.000 View mutations
21 A 19 0 19 0.004 0.957 View mutations
22 A 19 0 19 0.004 0.894 View mutations
23 A 7 12 19 0.654 0.385 View mutations
24 Q 16 3 19 0.142 0.748 View mutations
25 E 19 0 19 0.072 0.827 View mutations