P21912 (SDHB)

Overview
Predicted structure (AF):
AF-P21912-F1-model_v4
Uniprot entry:
P21912
Gene:
SDHB
Protein length:
280 residues
Mutations found:
5319
Benign based on D2Deep prediction:
3093 out of 5319 mutations
Pathogenic based on D2Deep prediction:
2226 out of 5319 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5319 mutations across 280 unique positions. There are 3093 benign and 2226 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 18 0 18 0.032 0.599 View mutations
2 A 17 2 19 0.131 0.684 View mutations
3 A 15 4 19 0.244 0.590 View mutations
4 V 14 5 19 0.257 0.583 View mutations
5 V 13 6 19 0.263 0.559 View mutations
6 A 19 0 19 0.005 0.739 View mutations
7 L 19 0 19 0.001 0.780 View mutations
8 S 19 0 19 0.031 0.792 View mutations
9 L 19 0 19 0.036 0.767 View mutations
10 R 18 1 19 0.062 0.781 View mutations
11 R 19 0 19 0.009 0.836 View mutations
12 R 19 0 19 0.000 0.827 View mutations
13 L 18 1 19 0.071 0.803 View mutations
14 P 19 0 19 0.006 0.832 View mutations
15 A 19 0 19 0.010 0.840 View mutations
16 T 14 5 19 0.243 0.669 View mutations
17 T 17 2 19 0.148 0.785 View mutations
18 L 18 1 19 0.054 0.836 View mutations
19 G 19 0 19 0.003 0.912 View mutations
20 G 19 0 19 0.002 0.895 View mutations
21 A 19 0 19 0.002 0.917 View mutations
22 C 19 0 19 0.000 0.932 View mutations
23 L 19 0 19 0.004 0.950 View mutations
24 Q 19 0 19 0.000 0.967 View mutations
25 A 19 0 19 0.003 0.943 View mutations