P21912 (SDHB)

Overview
Predicted structure (AF):
AF-P21912-F1-model_v4
Uniprot entry:
P21912
Gene:
SDHB
Protein length:
280 residues
Mutations found:
5319
Benign based on D2Deep prediction:
3093 out of 5319 mutations
Pathogenic based on D2Deep prediction:
2226 out of 5319 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5319 mutations across 280 unique positions. There are 3093 benign and 2226 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 S 19 0 19 0.004 0.974 View mutations
27 R 19 0 19 0.007 1.000 View mutations
28 G 19 0 19 0.000 0.990 View mutations
29 A 19 0 19 0.010 0.970 View mutations
30 Q 19 0 19 0.000 0.990 View mutations
31 T 19 0 19 0.010 0.930 View mutations
32 A 19 0 19 0.054 0.951 View mutations
33 A 18 1 19 0.065 0.846 View mutations
34 A 19 0 19 0.060 0.881 View mutations
35 T 19 0 19 0.009 0.864 View mutations
36 A 19 0 19 0.025 0.889 View mutations
37 P 19 0 19 0.006 0.860 View mutations
38 R 19 0 19 0.024 0.839 View mutations
39 I 18 1 19 0.065 0.819 View mutations
40 K 19 0 19 0.006 0.779 View mutations
41 K 18 1 19 0.044 0.829 View mutations
42 F 19 0 19 0.028 0.597 View mutations
43 A 19 0 19 0.003 0.817 View mutations
44 I 8 11 19 0.630 0.433 View mutations
45 Y 1 18 19 0.962 0.414 View mutations
46 R 0 19 19 0.996 0.553 View mutations
47 W 4 15 19 0.726 0.418 View mutations
48 D 18 1 19 0.105 0.529 View mutations
49 P 12 7 19 0.374 0.500 View mutations
50 D 5 14 19 0.749 0.402 View mutations