P21912 (SDHB)

Overview
Predicted structure (AF):
AF-P21912-F1-model_v4
Uniprot entry:
P21912
Gene:
SDHB
Protein length:
280 residues
Mutations found:
5319
Benign based on D2Deep prediction:
3093 out of 5319 mutations
Pathogenic based on D2Deep prediction:
2226 out of 5319 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5319 mutations across 280 unique positions. There are 3093 benign and 2226 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
251 R 13 6 19 0.369 0.447 View mutations
252 T 9 10 19 0.538 0.507 View mutations
253 C 0 19 19 1.000 0.867 View mutations
254 P 0 19 19 0.929 0.828 View mutations
255 K 2 17 19 0.897 0.658 View mutations
256 G 5 14 19 0.759 0.589 View mutations
257 L 0 19 19 1.000 0.808 View mutations
258 N 9 10 19 0.509 0.508 View mutations
259 P 0 19 19 0.980 0.811 View mutations
260 G 19 0 19 0.004 0.350 View mutations
261 K 18 1 19 0.110 0.401 View mutations
262 A 0 19 19 0.999 0.623 View mutations
263 I 13 6 19 0.330 0.406 View mutations
264 A 16 3 19 0.205 0.448 View mutations
265 E 13 6 19 0.325 0.407 View mutations
266 I 18 1 19 0.047 0.447 View mutations
267 K 2 17 19 0.910 0.546 View mutations
268 K 14 5 19 0.275 0.560 View mutations
269 M 17 2 19 0.164 0.578 View mutations
270 M 11 8 19 0.370 0.458 View mutations
271 A 17 2 19 0.107 0.499 View mutations
272 T 19 0 19 0.002 0.638 View mutations
273 Y 19 0 19 0.002 0.677 View mutations
274 K 17 2 19 0.119 0.612 View mutations
275 E 19 0 19 0.006 0.642 View mutations