P21912 (SDHB)

Overview
Predicted structure (AF):
AF-P21912-F1-model_v4
Uniprot entry:
P21912
Gene:
SDHB
Protein length:
280 residues
Mutations found:
5319
Benign based on D2Deep prediction:
3093 out of 5319 mutations
Pathogenic based on D2Deep prediction:
2226 out of 5319 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5319 mutations across 280 unique positions. There are 3093 benign and 2226 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
201 W 0 19 19 1.000 0.679 View mutations
202 N 9 10 19 0.512 0.505 View mutations
203 G 19 0 19 0.017 0.448 View mutations
204 D 19 0 19 0.000 0.446 View mutations
205 K 17 2 19 0.125 0.391 View mutations
206 Y 1 18 19 0.948 0.707 View mutations
207 L 0 19 19 1.000 0.712 View mutations
208 G 1 18 19 0.948 0.752 View mutations
209 P 0 19 19 0.988 0.798 View mutations
210 A 19 0 19 0.054 0.248 View mutations
211 V 9 10 19 0.520 0.503 View mutations
212 L 0 19 19 1.000 0.743 View mutations
213 M 3 16 19 0.859 0.580 View mutations
214 Q 0 19 19 0.985 0.631 View mutations
215 A 3 16 19 0.877 0.587 View mutations
216 Y 0 19 19 0.975 0.602 View mutations
217 R 0 19 19 0.994 0.773 View mutations
218 W 0 19 19 0.981 0.707 View mutations
219 M 4 15 19 0.780 0.586 View mutations
220 I 19 0 19 0.015 0.422 View mutations
221 D 2 17 19 0.877 0.723 View mutations
222 S 7 12 19 0.595 0.562 View mutations
223 R 19 0 19 0.007 0.284 View mutations
224 D 14 5 19 0.246 0.471 View mutations
225 D 19 0 19 0.006 0.451 View mutations