P23769 (GATA2)

Overview
Predicted structure (AF):
AF-P23769-F1-model_v4
Uniprot entry:
P23769
Gene:
GATA2
Protein length:
480 residues
Mutations found:
9119
Benign based on D2Deep prediction:
4824 out of 9119 mutations
Pathogenic based on D2Deep prediction:
4295 out of 9119 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 9119 mutations across 480 unique positions. There are 4824 benign and 4295 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 0 18 18 0.999 0.645 View mutations
2 E 3 16 19 0.797 0.519 View mutations
3 V 1 18 19 0.972 0.491 View mutations
4 A 7 12 19 0.604 0.427 View mutations
5 P 18 1 19 0.071 0.461 View mutations
6 E 15 4 19 0.237 0.491 View mutations
7 Q 19 0 19 0.000 0.465 View mutations
8 P 19 0 19 0.024 0.366 View mutations
9 R 18 1 19 0.114 0.397 View mutations
10 W 15 4 19 0.281 0.499 View mutations
11 M 19 0 19 0.021 0.494 View mutations
12 A 10 9 19 0.490 0.456 View mutations
13 H 13 6 19 0.292 0.444 View mutations
14 P 7 12 19 0.643 0.442 View mutations
15 A 19 0 19 0.002 0.376 View mutations
16 V 19 0 19 0.001 0.475 View mutations
17 L 7 12 19 0.551 0.505 View mutations
18 N 2 17 19 0.931 0.467 View mutations
19 A 5 14 19 0.763 0.506 View mutations
20 Q 15 4 19 0.275 0.410 View mutations
21 H 1 18 19 0.937 0.428 View mutations
22 P 9 10 19 0.545 0.430 View mutations
23 D 1 18 19 0.951 0.516 View mutations
24 S 1 18 19 0.892 0.413 View mutations
25 H 0 19 19 0.996 0.424 View mutations