P23769 (GATA2)

Overview
Predicted structure (AF):
AF-P23769-F1-model_v4
Uniprot entry:
P23769
Gene:
GATA2
Protein length:
480 residues
Mutations found:
9119
Benign based on D2Deep prediction:
4824 out of 9119 mutations
Pathogenic based on D2Deep prediction:
4295 out of 9119 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9119 mutations across 480 unique positions. There are 4824 benign and 4295 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 H 0 19 19 0.973 0.600 View mutations
52 L 0 19 19 1.000 0.633 View mutations
53 D 0 19 19 0.992 0.580 View mutations
54 S 9 10 19 0.614 0.505 View mutations
55 Q 18 1 19 0.067 0.443 View mutations
56 G 14 5 19 0.409 0.446 View mutations
57 N 0 19 19 0.978 0.511 View mutations
58 P 12 7 19 0.404 0.469 View mutations
59 Y 2 17 19 0.886 0.427 View mutations
60 Y 3 16 19 0.832 0.425 View mutations
61 A 5 14 19 0.723 0.416 View mutations
62 N 1 18 19 0.929 0.360 View mutations
63 P 17 2 19 0.113 0.541 View mutations
64 A 14 5 19 0.256 0.588 View mutations
65 H 14 5 19 0.294 0.591 View mutations
66 A 15 4 19 0.180 0.553 View mutations
67 R 11 8 19 0.467 0.475 View mutations
68 A 10 9 19 0.418 0.447 View mutations
69 R 17 2 19 0.133 0.489 View mutations
70 V 17 2 19 0.103 0.496 View mutations
71 S 6 13 19 0.633 0.425 View mutations
72 Y 8 11 19 0.592 0.436 View mutations
73 S 1 18 19 0.927 0.444 View mutations
74 P 10 9 19 0.516 0.438 View mutations
75 A 6 13 19 0.682 0.425 View mutations