P23769 (GATA2)

Overview
Predicted structure (AF):
AF-P23769-F1-model_v4
Uniprot entry:
P23769
Gene:
GATA2
Protein length:
480 residues
Mutations found:
9119
Benign based on D2Deep prediction:
4824 out of 9119 mutations
Pathogenic based on D2Deep prediction:
4295 out of 9119 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9119 mutations across 480 unique positions. There are 4824 benign and 4295 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 H 6 13 19 0.660 0.426 View mutations
27 P 16 3 19 0.178 0.479 View mutations
28 G 16 3 19 0.235 0.412 View mutations
29 L 9 10 19 0.493 0.430 View mutations
30 A 9 10 19 0.556 0.430 View mutations
31 H 12 7 19 0.380 0.429 View mutations
32 N 6 13 19 0.667 0.441 View mutations
33 Y 1 18 19 0.972 0.547 View mutations
34 M 13 6 19 0.295 0.410 View mutations
35 E 1 18 19 0.920 0.582 View mutations
36 P 8 11 19 0.542 0.503 View mutations
37 A 16 3 19 0.197 0.428 View mutations
38 Q 1 18 19 0.892 0.514 View mutations
39 L 1 18 19 0.931 0.524 View mutations
40 L 0 19 19 0.967 0.505 View mutations
41 P 1 18 19 0.939 0.515 View mutations
42 P 13 6 19 0.299 0.477 View mutations
43 D 18 1 19 0.048 0.398 View mutations
44 E 1 18 19 0.952 0.619 View mutations
45 V 1 18 19 0.900 0.566 View mutations
46 D 10 9 19 0.503 0.490 View mutations
47 V 9 10 19 0.535 0.506 View mutations
48 F 4 15 19 0.808 0.549 View mutations
49 F 1 18 19 0.906 0.616 View mutations
50 N 2 17 19 0.893 0.594 View mutations