P23769 (GATA2)

Overview
Predicted structure (AF):
AF-P23769-F1-model_v4
Uniprot entry:
P23769
Gene:
GATA2
Protein length:
480 residues
Mutations found:
9119
Benign based on D2Deep prediction:
4824 out of 9119 mutations
Pathogenic based on D2Deep prediction:
4295 out of 9119 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 9119 mutations across 480 unique positions. There are 4824 benign and 4295 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
451 H 13 6 19 0.364 0.453 View mutations
452 I 9 10 19 0.569 0.505 View mutations
453 L 4 15 19 0.789 0.573 View mutations
454 P 14 5 19 0.244 0.480 View mutations
455 T 7 12 19 0.643 0.534 View mutations
456 P 1 18 19 0.900 0.653 View mutations
457 T 3 16 19 0.821 0.570 View mutations
458 P 0 19 19 0.916 0.636 View mutations
459 I 8 11 19 0.560 0.522 View mutations
460 H 17 2 19 0.112 0.393 View mutations
461 P 18 1 19 0.073 0.437 View mutations
462 S 16 3 19 0.168 0.400 View mutations
463 S 19 0 19 0.017 0.550 View mutations
464 S 19 0 19 0.002 0.544 View mutations
465 L 10 9 19 0.423 0.451 View mutations
466 S 17 2 19 0.118 0.568 View mutations
467 F 7 12 19 0.647 0.443 View mutations
468 G 16 3 19 0.151 0.485 View mutations
469 H 10 9 19 0.534 0.443 View mutations
470 P 0 19 19 0.953 0.477 View mutations
471 H 0 19 19 0.987 0.457 View mutations
472 P 15 4 19 0.233 0.401 View mutations
473 S 18 1 19 0.057 0.386 View mutations
474 S 18 1 19 0.151 0.482 View mutations
475 M 12 7 19 0.347 0.480 View mutations