P23769 (GATA2)

Overview
Predicted structure (AF):
AF-P23769-F1-model_v4
Uniprot entry:
P23769
Gene:
GATA2
Protein length:
480 residues
Mutations found:
9119
Benign based on D2Deep prediction:
4824 out of 9119 mutations
Pathogenic based on D2Deep prediction:
4295 out of 9119 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9119 mutations across 480 unique positions. There are 4824 benign and 4295 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
426 S 10 9 19 0.480 0.448 View mutations
427 P 1 18 19 0.963 0.405 View mutations
428 F 0 19 19 1.000 0.476 View mutations
429 S 11 8 19 0.434 0.466 View mutations
430 A 16 3 19 0.203 0.592 View mutations
431 A 18 1 19 0.080 0.608 View mutations
432 A 15 4 19 0.252 0.521 View mutations
433 L 18 1 19 0.053 0.515 View mutations
434 A 15 4 19 0.244 0.536 View mutations
435 G 18 1 19 0.067 0.596 View mutations
436 H 19 0 19 0.000 0.520 View mutations
437 M 19 0 19 0.000 0.561 View mutations
438 A 14 5 19 0.269 0.600 View mutations
439 P 6 13 19 0.579 0.383 View mutations
440 V 6 13 19 0.725 0.395 View mutations
441 G 7 12 19 0.708 0.413 View mutations
442 H 15 4 19 0.202 0.439 View mutations
443 L 19 0 19 0.010 0.458 View mutations
444 P 12 7 19 0.421 0.431 View mutations
445 P 19 0 19 0.027 0.375 View mutations
446 F 19 0 19 0.009 0.471 View mutations
447 S 19 0 19 0.026 0.364 View mutations
448 H 18 1 19 0.075 0.491 View mutations
449 S 9 10 19 0.471 0.429 View mutations
450 G 8 11 19 0.598 0.508 View mutations