P23769 (GATA2)

Overview
Predicted structure (AF):
AF-P23769-F1-model_v4
Uniprot entry:
P23769
Gene:
GATA2
Protein length:
480 residues
Mutations found:
9119
Benign based on D2Deep prediction:
4824 out of 9119 mutations
Pathogenic based on D2Deep prediction:
4295 out of 9119 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9119 mutations across 480 unique positions. There are 4824 benign and 4295 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
401 S 0 19 19 0.947 0.663 View mutations
402 N 8 11 19 0.546 0.518 View mutations
403 K 5 14 19 0.696 0.548 View mutations
404 S 2 17 19 0.854 0.528 View mutations
405 K 17 2 19 0.111 0.485 View mutations
406 K 19 0 19 0.004 0.449 View mutations
407 S 19 0 19 0.001 0.551 View mutations
408 K 16 3 19 0.172 0.485 View mutations
409 K 19 0 19 0.004 0.519 View mutations
410 G 13 6 19 0.320 0.536 View mutations
411 A 10 9 19 0.470 0.470 View mutations
412 E 0 19 19 0.974 0.424 View mutations
413 C 1 18 19 0.861 0.338 View mutations
414 F 4 15 19 0.738 0.438 View mutations
415 E 16 3 19 0.165 0.399 View mutations
416 E 0 19 19 0.990 0.463 View mutations
417 L 16 3 19 0.189 0.421 View mutations
418 S 11 8 19 0.400 0.451 View mutations
419 K 16 3 19 0.179 0.467 View mutations
420 C 7 12 19 0.646 0.419 View mutations
421 M 19 0 19 0.052 0.506 View mutations
422 Q 18 1 19 0.053 0.574 View mutations
423 E 2 17 19 0.772 0.416 View mutations
424 K 1 18 19 0.916 0.413 View mutations
425 S 19 0 19 0.029 0.630 View mutations