P23769 (GATA2)

Overview
Predicted structure (AF):
AF-P23769-F1-model_v4
Uniprot entry:
P23769
Gene:
GATA2
Protein length:
480 residues
Mutations found:
9119
Benign based on D2Deep prediction:
4824 out of 9119 mutations
Pathogenic based on D2Deep prediction:
4295 out of 9119 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 9119 mutations across 480 unique positions. There are 4824 benign and 4295 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 H 4 15 19 0.756 0.412 View mutations
77 A 14 5 19 0.236 0.504 View mutations
78 R 0 19 19 0.980 0.287 View mutations
79 L 3 16 19 0.756 0.350 View mutations
80 T 4 15 19 0.791 0.358 View mutations
81 G 6 13 19 0.610 0.423 View mutations
82 G 2 17 19 0.843 0.377 View mutations
83 Q 12 7 19 0.322 0.459 View mutations
84 M 19 0 19 0.054 0.373 View mutations
85 C 5 14 19 0.680 0.431 View mutations
86 R 19 0 19 0.071 0.402 View mutations
87 P 10 9 19 0.511 0.498 View mutations
88 H 16 3 19 0.253 0.459 View mutations
89 L 19 0 19 0.011 0.480 View mutations
90 L 19 0 19 0.003 0.484 View mutations
91 H 19 0 19 0.009 0.496 View mutations
92 S 19 0 19 0.000 0.368 View mutations
93 P 19 0 19 0.035 0.468 View mutations
94 G 19 0 19 0.021 0.490 View mutations
95 L 13 6 19 0.376 0.410 View mutations
96 P 13 6 19 0.314 0.494 View mutations
97 W 18 1 19 0.042 0.423 View mutations
98 L 18 1 19 0.060 0.457 View mutations
99 D 16 3 19 0.180 0.439 View mutations
100 G 15 4 19 0.264 0.439 View mutations