P23771-2 (GATA3)

Overview
Predicted structure (AF):
AF-P23771-2-F1-model_v4
Uniprot entry:
P23771-2
Gene:
GATA3
Protein length:
444 residues
Mutations found:
8435
Benign based on D2Deep prediction:
3875 out of 8435 mutations
Pathogenic based on D2Deep prediction:
4560 out of 8435 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 8435 mutations across 444 unique positions. There are 3875 benign and 4560 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 0 18 18 0.984 0.557 View mutations
2 E 8 11 19 0.580 0.436 View mutations
3 V 0 19 19 1.000 0.424 View mutations
4 T 9 10 19 0.546 0.447 View mutations
5 A 16 3 19 0.228 0.519 View mutations
6 D 15 4 19 0.225 0.404 View mutations
7 Q 19 0 19 0.001 0.500 View mutations
8 P 18 1 19 0.057 0.443 View mutations
9 R 8 11 19 0.492 0.435 View mutations
10 W 0 19 19 0.968 0.412 View mutations
11 V 18 1 19 0.043 0.586 View mutations
12 S 4 15 19 0.765 0.345 View mutations
13 H 14 5 19 0.283 0.584 View mutations
14 H 8 11 19 0.490 0.429 View mutations
15 H 19 0 19 0.011 0.736 View mutations
16 P 19 0 19 0.000 0.634 View mutations
17 A 9 10 19 0.539 0.445 View mutations
18 V 7 12 19 0.653 0.436 View mutations
19 L 3 16 19 0.762 0.437 View mutations
20 N 16 3 19 0.170 0.478 View mutations
21 G 4 15 19 0.795 0.433 View mutations
22 Q 12 7 19 0.416 0.456 View mutations
23 H 0 19 19 0.996 0.364 View mutations
24 P 1 18 19 0.908 0.391 View mutations
25 D 1 18 19 0.927 0.428 View mutations