P23771-2 (GATA3)

Overview
Predicted structure (AF):
AF-P23771-2-F1-model_v4
Uniprot entry:
P23771-2
Gene:
GATA3
Protein length:
444 residues
Mutations found:
8435
Benign based on D2Deep prediction:
3875 out of 8435 mutations
Pathogenic based on D2Deep prediction:
4560 out of 8435 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 8435 mutations across 444 unique positions. There are 3875 benign and 4560 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
426 P 14 5 19 0.244 0.528 View mutations
427 S 2 17 19 0.847 0.329 View mutations
428 S 1 18 19 0.958 0.316 View mutations
429 L 17 2 19 0.181 0.564 View mutations
430 S 17 2 19 0.122 0.540 View mutations
431 F 8 11 19 0.616 0.436 View mutations
432 G 14 5 19 0.299 0.435 View mutations
433 P 19 0 19 0.003 0.503 View mutations
434 H 15 4 19 0.243 0.412 View mutations
435 H 18 1 19 0.069 0.420 View mutations
436 P 19 0 19 0.005 0.443 View mutations
437 S 18 1 19 0.048 0.457 View mutations
438 S 3 16 19 0.814 0.463 View mutations
439 M 6 13 19 0.694 0.513 View mutations
440 V 1 18 19 0.955 0.525 View mutations
441 T 0 19 19 0.993 0.485 View mutations
442 A 14 5 19 0.260 0.475 View mutations
443 M 17 2 19 0.172 0.463 View mutations
444 G 6 13 19 0.718 0.516 View mutations