P23771-2 (GATA3)

Overview
Predicted structure (AF):
AF-P23771-2-F1-model_v4
Uniprot entry:
P23771-2
Gene:
GATA3
Protein length:
444 residues
Mutations found:
8435
Benign based on D2Deep prediction:
3875 out of 8435 mutations
Pathogenic based on D2Deep prediction:
4560 out of 8435 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 8435 mutations across 444 unique positions. There are 3875 benign and 4560 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 T 13 6 19 0.331 0.517 View mutations
27 H 16 3 19 0.173 0.527 View mutations
28 H 12 7 19 0.446 0.483 View mutations
29 P 4 15 19 0.786 0.365 View mutations
30 G 7 12 19 0.634 0.419 View mutations
31 L 10 9 19 0.490 0.445 View mutations
32 S 12 7 19 0.385 0.464 View mutations
33 H 1 18 19 0.922 0.403 View mutations
34 S 15 4 19 0.289 0.497 View mutations
35 Y 1 18 19 0.891 0.436 View mutations
36 M 19 0 19 0.027 0.504 View mutations
37 D 16 3 19 0.165 0.392 View mutations
38 A 10 9 19 0.506 0.443 View mutations
39 A 3 16 19 0.850 0.366 View mutations
40 Q 6 13 19 0.651 0.424 View mutations
41 Y 2 17 19 0.847 0.430 View mutations
42 P 15 4 19 0.183 0.455 View mutations
43 L 18 1 19 0.051 0.497 View mutations
44 P 6 13 19 0.633 0.432 View mutations
45 E 1 18 19 0.946 0.504 View mutations
46 E 2 17 19 0.828 0.507 View mutations
47 V 9 10 19 0.518 0.437 View mutations
48 D 0 19 19 0.996 0.569 View mutations
49 V 1 18 19 0.928 0.485 View mutations
50 L 3 16 19 0.847 0.461 View mutations