P23771-2 (GATA3)

Overview
Predicted structure (AF):
AF-P23771-2-F1-model_v4
Uniprot entry:
P23771-2
Gene:
GATA3
Protein length:
444 residues
Mutations found:
8435
Benign based on D2Deep prediction:
3875 out of 8435 mutations
Pathogenic based on D2Deep prediction:
4560 out of 8435 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 8435 mutations across 444 unique positions. There are 3875 benign and 4560 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 F 0 19 19 0.999 0.531 View mutations
52 N 0 19 19 0.980 0.564 View mutations
53 I 0 19 19 0.988 0.469 View mutations
54 D 1 18 19 0.945 0.462 View mutations
55 G 19 0 19 0.008 0.351 View mutations
56 Q 14 5 19 0.286 0.406 View mutations
57 G 3 16 19 0.827 0.443 View mutations
58 N 17 2 19 0.172 0.523 View mutations
59 H 16 3 19 0.169 0.611 View mutations
60 V 8 11 19 0.576 0.429 View mutations
61 P 8 11 19 0.631 0.427 View mutations
62 P 5 14 19 0.757 0.421 View mutations
63 Y 6 13 19 0.629 0.413 View mutations
64 Y 9 10 19 0.480 0.444 View mutations
65 G 12 7 19 0.412 0.480 View mutations
66 N 9 10 19 0.532 0.440 View mutations
67 S 6 13 19 0.684 0.395 View mutations
68 V 5 14 19 0.686 0.383 View mutations
69 R 18 1 19 0.079 0.669 View mutations
70 A 17 2 19 0.098 0.660 View mutations
71 T 11 8 19 0.440 0.531 View mutations
72 V 16 3 19 0.287 0.610 View mutations
73 Q 2 17 19 0.862 0.272 View mutations
74 R 1 18 19 0.937 0.294 View mutations
75 Y 1 18 19 0.933 0.325 View mutations