P23771-2 (GATA3)

Overview
Predicted structure (AF):
AF-P23771-2-F1-model_v4
Uniprot entry:
P23771-2
Gene:
GATA3
Protein length:
444 residues
Mutations found:
8435
Benign based on D2Deep prediction:
3875 out of 8435 mutations
Pathogenic based on D2Deep prediction:
4560 out of 8435 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 8435 mutations across 444 unique positions. There are 3875 benign and 4560 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
376 C 15 4 19 0.202 0.578 View mutations
377 K 12 7 19 0.393 0.482 View mutations
378 K 1 18 19 0.935 0.335 View mutations
379 V 11 8 19 0.390 0.517 View mutations
380 H 3 16 19 0.845 0.292 View mutations
381 D 9 10 19 0.552 0.437 View mutations
382 S 10 9 19 0.468 0.463 View mutations
383 L 2 17 19 0.883 0.369 View mutations
384 E 19 0 19 0.001 0.457 View mutations
385 D 17 2 19 0.138 0.397 View mutations
386 F 7 12 19 0.637 0.424 View mutations
387 P 9 10 19 0.536 0.448 View mutations
388 K 19 0 19 0.003 0.550 View mutations
389 N 12 7 19 0.408 0.507 View mutations
390 S 19 0 19 0.023 0.671 View mutations
391 S 13 6 19 0.333 0.511 View mutations
392 F 14 5 19 0.256 0.503 View mutations
393 N 15 4 19 0.215 0.594 View mutations
394 P 15 4 19 0.221 0.610 View mutations
395 A 19 0 19 0.000 0.698 View mutations
396 A 19 0 19 0.009 0.583 View mutations
397 L 11 8 19 0.438 0.460 View mutations
398 S 5 14 19 0.706 0.375 View mutations
399 R 19 0 19 0.033 0.574 View mutations
400 H 11 8 19 0.430 0.452 View mutations