P23771-2 (GATA3)

Overview
Predicted structure (AF):
AF-P23771-2-F1-model_v4
Uniprot entry:
P23771-2
Gene:
GATA3
Protein length:
444 residues
Mutations found:
8435
Benign based on D2Deep prediction:
3875 out of 8435 mutations
Pathogenic based on D2Deep prediction:
4560 out of 8435 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 8435 mutations across 444 unique positions. There are 3875 benign and 4560 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
401 M 1 18 19 0.869 0.339 View mutations
402 S 19 0 19 0.083 0.755 View mutations
403 S 17 2 19 0.152 0.641 View mutations
404 L 3 16 19 0.840 0.326 View mutations
405 S 17 2 19 0.085 0.623 View mutations
406 H 19 0 19 0.000 0.600 View mutations
407 I 19 0 19 0.006 0.616 View mutations
408 S 4 15 19 0.785 0.428 View mutations
409 P 13 6 19 0.358 0.448 View mutations
410 F 1 18 19 0.926 0.478 View mutations
411 S 1 18 19 0.944 0.435 View mutations
412 H 0 19 19 1.000 0.492 View mutations
413 S 0 19 19 0.999 0.465 View mutations
414 S 5 14 19 0.702 0.532 View mutations
415 H 12 7 19 0.395 0.475 View mutations
416 M 0 19 19 0.996 0.600 View mutations
417 L 3 16 19 0.826 0.605 View mutations
418 T 6 13 19 0.693 0.513 View mutations
419 T 3 16 19 0.784 0.582 View mutations
420 P 0 19 19 0.996 0.649 View mutations
421 T 15 4 19 0.265 0.454 View mutations
422 P 16 3 19 0.178 0.420 View mutations
423 M 5 14 19 0.743 0.532 View mutations
424 H 2 17 19 0.918 0.562 View mutations
425 P 14 5 19 0.317 0.391 View mutations