P24385 (P24385)

Overview
Predicted structure (AF):
AF-P24385-F1-model_v4
Uniprot entry:
P24385
Gene:
P24385
Protein length:
295 residues
Mutations found:
5604
Benign based on D2Deep prediction:
3437 out of 5604 mutations
Pathogenic based on D2Deep prediction:
2167 out of 5604 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 5604 mutations across 295 unique positions. There are 3437 benign and 2167 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 E 1 18 19 0.949 0.619 View mutations
52 V 2 17 19 0.871 0.646 View mutations
53 L 14 5 19 0.309 0.416 View mutations
54 P 7 12 19 0.596 0.552 View mutations
55 S 19 0 19 0.000 0.499 View mutations
56 M 1 18 19 0.931 0.731 View mutations
57 R 0 19 19 1.000 0.755 View mutations
58 K 15 4 19 0.277 0.452 View mutations
59 I 5 14 19 0.726 0.505 View mutations
60 V 2 17 19 0.851 0.616 View mutations
61 A 1 18 19 0.944 0.626 View mutations
62 T 3 16 19 0.833 0.508 View mutations
63 W 9 10 19 0.545 0.504 View mutations
64 M 18 1 19 0.190 0.375 View mutations
65 L 3 16 19 0.834 0.639 View mutations
66 E 4 15 19 0.785 0.661 View mutations
67 V 0 19 19 0.986 0.782 View mutations
68 C 0 19 19 0.995 0.741 View mutations
69 E 11 8 19 0.409 0.459 View mutations
70 E 3 16 19 0.720 0.659 View mutations
71 Q 1 18 19 0.945 0.647 View mutations
72 K 7 12 19 0.606 0.530 View mutations
73 C 0 19 19 0.995 0.656 View mutations
74 E 1 18 19 0.939 0.592 View mutations
75 E 2 17 19 0.898 0.634 View mutations