P24385 (P24385)

Overview
Predicted structure (AF):
AF-P24385-F1-model_v4
Uniprot entry:
P24385
Gene:
P24385
Protein length:
295 residues
Mutations found:
5604
Benign based on D2Deep prediction:
3437 out of 5604 mutations
Pathogenic based on D2Deep prediction:
2167 out of 5604 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 5604 mutations across 295 unique positions. There are 3437 benign and 2167 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 R 19 0 19 0.044 0.471 View mutations
27 V 19 0 19 0.025 0.335 View mutations
28 L 19 0 19 0.039 0.335 View mutations
29 R 17 2 19 0.102 0.376 View mutations
30 A 15 4 19 0.215 0.425 View mutations
31 M 9 10 19 0.512 0.511 View mutations
32 L 17 2 19 0.112 0.254 View mutations
33 K 15 4 19 0.256 0.409 View mutations
34 A 18 1 19 0.044 0.484 View mutations
35 E 0 19 19 0.993 0.764 View mutations
36 E 18 1 19 0.192 0.337 View mutations
37 T 19 0 19 0.005 0.467 View mutations
38 C 5 14 19 0.717 0.520 View mutations
39 A 10 9 19 0.497 0.496 View mutations
40 P 1 18 19 0.921 0.718 View mutations
41 S 15 4 19 0.215 0.481 View mutations
42 V 19 0 19 0.000 0.449 View mutations
43 S 19 0 19 0.000 0.399 View mutations
44 Y 1 18 19 0.951 0.731 View mutations
45 F 0 19 19 1.000 0.782 View mutations
46 K 11 8 19 0.466 0.498 View mutations
47 C 15 4 19 0.294 0.459 View mutations
48 V 5 14 19 0.753 0.623 View mutations
49 Q 0 19 19 0.998 0.722 View mutations
50 K 3 16 19 0.842 0.508 View mutations