P25445 (P25445)

Overview
Predicted structure (AF):
AF-P25445-F1-model_v4
Uniprot entry:
P25445
Gene:
P25445
Protein length:
335 residues
Mutations found:
6364
Benign based on D2Deep prediction:
4666 out of 6364 mutations
Pathogenic based on D2Deep prediction:
1698 out of 6364 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 6364 mutations across 335 unique positions. There are 4666 benign and 1698 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
326 N 15 4 19 0.203 0.567 View mutations
327 F 18 1 19 0.063 0.655 View mutations
328 R 19 0 19 0.008 0.686 View mutations
329 N 19 0 19 0.062 0.601 View mutations
330 E 4 15 19 0.792 0.373 View mutations
331 I 17 2 19 0.146 0.602 View mutations
332 Q 10 9 19 0.511 0.458 View mutations
333 S 17 2 19 0.212 0.556 View mutations
334 L 4 15 19 0.725 0.364 View mutations
335 V 18 1 19 0.056 0.505 View mutations