P25445 (P25445)

Overview
Predicted structure (AF):
AF-P25445-F1-model_v4
Uniprot entry:
P25445
Gene:
P25445
Protein length:
335 residues
Mutations found:
6364
Benign based on D2Deep prediction:
4666 out of 6364 mutations
Pathogenic based on D2Deep prediction:
1698 out of 6364 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 6364 mutations across 335 unique positions. There are 4666 benign and 1698 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
301 A 19 0 19 0.015 0.470 View mutations
302 N 19 0 19 0.000 0.376 View mutations
303 L 16 3 19 0.191 0.486 View mutations
304 C 6 13 19 0.666 0.437 View mutations
305 T 19 0 19 0.000 0.354 View mutations
306 L 17 2 19 0.130 0.414 View mutations
307 A 16 3 19 0.190 0.413 View mutations
308 E 19 0 19 0.002 0.486 View mutations
309 K 19 0 19 0.002 0.462 View mutations
310 I 14 5 19 0.326 0.398 View mutations
311 Q 17 2 19 0.166 0.465 View mutations
312 T 19 0 19 0.002 0.497 View mutations
313 I 19 0 19 0.002 0.392 View mutations
314 I 16 3 19 0.141 0.424 View mutations
315 L 19 0 19 0.012 0.493 View mutations
316 K 19 0 19 0.000 0.511 View mutations
317 D 19 0 19 0.018 0.404 View mutations
318 I 19 0 19 0.002 0.525 View mutations
319 T 19 0 19 0.018 0.649 View mutations
320 S 19 0 19 0.006 0.689 View mutations
321 D 18 1 19 0.141 0.696 View mutations
322 S 19 0 19 0.013 0.679 View mutations
323 E 16 3 19 0.161 0.622 View mutations
324 N 13 6 19 0.331 0.543 View mutations
325 S 18 1 19 0.105 0.590 View mutations