P29992 (GNA11)

Overview
Predicted structure (AF):
AF-P29992-F1-model_v4
Uniprot entry:
P29992
Gene:
GNA11
Protein length:
359 residues
Mutations found:
6820
Benign based on D2Deep prediction:
3997 out of 6820 mutations
Pathogenic based on D2Deep prediction:
2823 out of 6820 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 6820 mutations across 359 unique positions. There are 3997 benign and 2823 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
226 I 2 17 19 0.903 0.672 View mutations
227 M 19 0 19 0.014 0.261 View mutations
228 F 0 19 19 0.980 0.751 View mutations
229 L 0 19 19 1.000 0.704 View mutations
230 V 1 18 19 0.947 0.655 View mutations
231 A 0 19 19 0.973 0.725 View mutations
232 L 1 18 19 0.953 0.688 View mutations
233 S 0 19 19 1.000 0.734 View mutations
234 E 0 19 19 1.000 0.763 View mutations
235 Y 4 15 19 0.721 0.672 View mutations
236 D 10 9 19 0.496 0.490 View mutations
237 Q 2 17 19 0.830 0.568 View mutations
238 V 2 17 19 0.898 0.522 View mutations
239 L 0 19 19 1.000 0.590 View mutations
240 V 18 1 19 0.083 0.437 View mutations
241 E 16 3 19 0.170 0.469 View mutations
242 S 16 3 19 0.222 0.516 View mutations
243 D 19 0 19 0.054 0.515 View mutations
244 N 19 0 19 0.001 0.518 View mutations
245 E 7 12 19 0.583 0.502 View mutations
246 N 2 17 19 0.893 0.545 View mutations
247 R 12 7 19 0.340 0.452 View mutations
248 M 1 18 19 0.952 0.569 View mutations
249 E 0 19 19 0.974 0.425 View mutations
250 E 0 19 19 0.977 0.737 View mutations