P29992 (GNA11)

Overview
Predicted structure (AF):
AF-P29992-F1-model_v4
Uniprot entry:
P29992
Gene:
GNA11
Protein length:
359 residues
Mutations found:
6820
Benign based on D2Deep prediction:
3997 out of 6820 mutations
Pathogenic based on D2Deep prediction:
2823 out of 6820 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 6820 mutations across 359 unique positions. There are 3997 benign and 2823 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
251 S 0 19 19 0.993 0.693 View mutations
252 K 8 11 19 0.569 0.437 View mutations
253 A 2 17 19 0.894 0.561 View mutations
254 L 16 3 19 0.206 0.318 View mutations
255 F 9 10 19 0.603 0.509 View mutations
256 R 7 12 19 0.595 0.418 View mutations
257 T 0 19 19 0.971 0.552 View mutations
258 I 11 8 19 0.472 0.488 View mutations
259 I 16 3 19 0.248 0.481 View mutations
260 T 19 0 19 0.003 0.467 View mutations
261 Y 6 13 19 0.689 0.428 View mutations
262 P 6 13 19 0.706 0.440 View mutations
263 W 8 11 19 0.615 0.506 View mutations
264 F 0 19 19 0.971 0.693 View mutations
265 Q 19 0 19 0.019 0.468 View mutations
266 N 19 0 19 0.001 0.478 View mutations
267 S 1 18 19 0.934 0.556 View mutations
268 S 11 8 19 0.451 0.479 View mutations
269 V 2 17 19 0.905 0.521 View mutations
270 I 0 19 19 0.995 0.796 View mutations
271 L 0 19 19 1.000 0.835 View mutations
272 F 9 10 19 0.476 0.521 View mutations
273 L 4 15 19 0.768 0.647 View mutations
274 N 0 19 19 0.999 0.889 View mutations
275 K 18 1 19 0.053 0.242 View mutations