P29992 (GNA11)

Overview
Predicted structure (AF):
AF-P29992-F1-model_v4
Uniprot entry:
P29992
Gene:
GNA11
Protein length:
359 residues
Mutations found:
6820
Benign based on D2Deep prediction:
3997 out of 6820 mutations
Pathogenic based on D2Deep prediction:
2823 out of 6820 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 6820 mutations across 359 unique positions. There are 3997 benign and 2823 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
276 K 5 14 19 0.751 0.508 View mutations
277 D 19 0 19 0.003 0.228 View mutations
278 L 19 0 19 0.003 0.259 View mutations
279 L 8 11 19 0.593 0.535 View mutations
280 E 16 3 19 0.168 0.481 View mutations
281 D 2 17 19 0.905 0.585 View mutations
282 K 5 14 19 0.723 0.617 View mutations
283 I 4 15 19 0.736 0.626 View mutations
284 L 6 13 19 0.677 0.426 View mutations
285 Y 16 3 19 0.173 0.431 View mutations
286 S 18 1 19 0.065 0.277 View mutations
287 H 19 0 19 0.013 0.370 View mutations
288 L 1 18 19 0.946 0.713 View mutations
289 V 19 0 19 0.011 0.490 View mutations
290 D 11 8 19 0.439 0.487 View mutations
291 Y 8 11 19 0.596 0.515 View mutations
292 F 1 18 19 0.960 0.657 View mutations
293 P 19 0 19 0.000 0.318 View mutations
294 E 13 6 19 0.318 0.498 View mutations
295 F 19 0 19 0.000 0.401 View mutations
296 D 19 0 19 0.000 0.447 View mutations
297 G 1 18 19 0.870 0.595 View mutations
298 P 13 6 19 0.333 0.423 View mutations
299 Q 17 2 19 0.122 0.463 View mutations
300 R 18 1 19 0.091 0.560 View mutations