P29992 (GNA11)

Overview
Predicted structure (AF):
AF-P29992-F1-model_v4
Uniprot entry:
P29992
Gene:
GNA11
Protein length:
359 residues
Mutations found:
6820
Benign based on D2Deep prediction:
3997 out of 6820 mutations
Pathogenic based on D2Deep prediction:
2823 out of 6820 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 6820 mutations across 359 unique positions. There are 3997 benign and 2823 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
301 D 19 0 19 0.015 0.485 View mutations
302 A 19 0 19 0.000 0.555 View mutations
303 Q 18 1 19 0.076 0.688 View mutations
304 A 10 9 19 0.477 0.447 View mutations
305 A 19 0 19 0.000 0.369 View mutations
306 R 19 0 19 0.003 0.549 View mutations
307 E 19 0 19 0.002 0.608 View mutations
308 F 19 0 19 0.044 0.379 View mutations
309 I 19 0 19 0.035 0.375 View mutations
310 L 15 4 19 0.229 0.462 View mutations
311 K 19 0 19 0.007 0.580 View mutations
312 M 19 0 19 0.000 0.571 View mutations
313 F 19 0 19 0.000 0.406 View mutations
314 V 19 0 19 0.013 0.581 View mutations
315 D 19 0 19 0.004 0.546 View mutations
316 L 19 0 19 0.000 0.571 View mutations
317 N 18 1 19 0.105 0.579 View mutations
318 P 19 0 19 0.001 0.565 View mutations
319 D 18 1 19 0.100 0.589 View mutations
320 S 19 0 19 0.010 0.649 View mutations
321 D 19 0 19 0.018 0.584 View mutations
322 K 14 5 19 0.307 0.430 View mutations
323 I 19 0 19 0.000 0.553 View mutations
324 I 2 17 19 0.914 0.463 View mutations
325 Y 2 17 19 0.886 0.599 View mutations