P30281 (P30281)

Overview
Predicted structure (AF):
AF-P30281-F1-model_v4
Uniprot entry:
P30281
Gene:
P30281
Protein length:
292 residues
Mutations found:
5547
Benign based on D2Deep prediction:
3019 out of 5547 mutations
Pathogenic based on D2Deep prediction:
2528 out of 5547 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 5547 mutations across 292 unique positions. There are 3019 benign and 2528 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
251 L 3 16 19 0.777 0.687 View mutations
252 R 18 1 19 0.061 0.392 View mutations
253 E 11 8 19 0.417 0.446 View mutations
254 S 17 2 19 0.123 0.472 View mutations
255 L 10 9 19 0.404 0.496 View mutations
256 R 19 0 19 0.045 0.577 View mutations
257 E 16 3 19 0.219 0.614 View mutations
258 A 17 2 19 0.088 0.616 View mutations
259 S 19 0 19 0.004 0.801 View mutations
260 Q 19 0 19 0.054 0.881 View mutations
261 T 19 0 19 0.010 0.890 View mutations
262 S 18 1 19 0.057 0.850 View mutations
263 S 18 1 19 0.047 0.837 View mutations
264 S 19 0 19 0.001 0.914 View mutations
265 P 19 0 19 0.002 0.972 View mutations
266 A 19 0 19 0.003 0.948 View mutations
267 P 19 0 19 0.053 0.976 View mutations
268 K 19 0 19 0.051 0.950 View mutations
269 A 19 0 19 0.040 0.974 View mutations
270 P 19 0 19 0.032 0.977 View mutations
271 R 19 0 19 0.059 1.000 View mutations
272 G 19 0 19 0.002 0.986 View mutations
273 S 19 0 19 0.006 0.903 View mutations
274 S 18 1 19 0.065 0.838 View mutations
275 S 19 0 19 0.017 0.881 View mutations