P30281 (P30281)

Overview
Predicted structure (AF):
AF-P30281-F1-model_v4
Uniprot entry:
P30281
Gene:
P30281
Protein length:
292 residues
Mutations found:
5547
Benign based on D2Deep prediction:
3019 out of 5547 mutations
Pathogenic based on D2Deep prediction:
2528 out of 5547 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5547 mutations across 292 unique positions. There are 3019 benign and 2528 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
226 T 8 11 19 0.548 0.504 View mutations
227 E 19 0 19 0.001 0.445 View mutations
228 L 13 6 19 0.345 0.415 View mutations
229 L 0 19 19 1.000 0.723 View mutations
230 A 3 16 19 0.823 0.525 View mutations
231 G 18 1 19 0.053 0.389 View mutations
232 I 2 17 19 0.884 0.624 View mutations
233 T 0 19 19 1.000 0.724 View mutations
234 G 3 16 19 0.826 0.553 View mutations
235 T 17 2 19 0.151 0.362 View mutations
236 E 19 0 19 0.002 0.317 View mutations
237 V 12 7 19 0.395 0.478 View mutations
238 D 0 19 19 0.984 0.608 View mutations
239 C 3 16 19 0.799 0.574 View mutations
240 L 1 18 19 0.911 0.776 View mutations
241 R 16 3 19 0.191 0.481 View mutations
242 A 15 4 19 0.261 0.448 View mutations
243 C 0 19 19 0.997 0.788 View mutations
244 Q 19 0 19 0.024 0.281 View mutations
245 E 0 19 19 0.983 0.684 View mutations
246 Q 3 16 19 0.785 0.577 View mutations
247 I 18 1 19 0.112 0.158 View mutations
248 E 4 15 19 0.795 0.603 View mutations
249 A 9 10 19 0.492 0.432 View mutations
250 A 8 11 19 0.534 0.527 View mutations