P30281 (P30281)

Overview
Predicted structure (AF):
AF-P30281-F1-model_v4
Uniprot entry:
P30281
Gene:
P30281
Protein length:
292 residues
Mutations found:
5547
Benign based on D2Deep prediction:
3019 out of 5547 mutations
Pathogenic based on D2Deep prediction:
2528 out of 5547 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5547 mutations across 292 unique positions. There are 3019 benign and 2528 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
201 S 0 19 19 1.000 0.864 View mutations
202 M 12 7 19 0.422 0.462 View mutations
203 I 17 2 19 0.097 0.105 View mutations
204 A 19 0 19 0.000 0.146 View mutations
205 T 8 11 19 0.544 0.527 View mutations
206 G 2 17 19 0.920 0.681 View mutations
207 S 0 19 19 0.954 0.836 View mutations
208 I 6 13 19 0.661 0.594 View mutations
209 G 10 9 19 0.549 0.490 View mutations
210 A 19 0 19 0.002 0.190 View mutations
211 A 6 13 19 0.767 0.613 View mutations
212 V 2 17 19 0.885 0.542 View mutations
213 Q 17 2 19 0.178 0.387 View mutations
214 G 7 12 19 0.623 0.542 View mutations
215 L 19 0 19 0.020 0.459 View mutations
216 G 10 9 19 0.462 0.468 View mutations
217 A 19 0 19 0.043 0.723 View mutations
218 C 18 1 19 0.066 0.685 View mutations
219 S 19 0 19 0.019 0.647 View mutations
220 M 19 0 19 0.001 0.649 View mutations
221 S 19 0 19 0.004 0.597 View mutations
222 G 19 0 19 0.017 0.571 View mutations
223 D 19 0 19 0.000 0.516 View mutations
224 E 18 1 19 0.111 0.561 View mutations
225 L 3 16 19 0.817 0.520 View mutations