P30281 (P30281)

Overview
Predicted structure (AF):
AF-P30281-F1-model_v4
Uniprot entry:
P30281
Gene:
P30281
Protein length:
292 residues
Mutations found:
5547
Benign based on D2Deep prediction:
3019 out of 5547 mutations
Pathogenic based on D2Deep prediction:
2528 out of 5547 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5547 mutations across 292 unique positions. There are 3019 benign and 2528 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 E 1 18 19 0.945 0.692 View mutations
77 V 2 17 19 0.896 0.722 View mutations
78 F 0 19 19 1.000 0.704 View mutations
79 P 0 19 19 0.992 0.661 View mutations
80 L 0 19 19 1.000 0.782 View mutations
81 A 0 19 19 0.998 0.748 View mutations
82 M 1 18 19 0.932 0.652 View mutations
83 N 0 19 19 1.000 0.751 View mutations
84 Y 5 14 19 0.769 0.563 View mutations
85 L 3 16 19 0.810 0.653 View mutations
86 D 3 16 19 0.811 0.722 View mutations
87 R 2 17 19 0.839 0.643 View mutations
88 Y 4 15 19 0.774 0.518 View mutations
89 L 11 8 19 0.405 0.468 View mutations
90 S 18 1 19 0.048 0.431 View mutations
91 C 17 2 19 0.132 0.462 View mutations
92 V 18 1 19 0.054 0.425 View mutations
93 P 14 5 19 0.332 0.408 View mutations
94 T 18 1 19 0.067 0.374 View mutations
95 R 14 5 19 0.243 0.538 View mutations
96 K 0 19 19 0.991 0.610 View mutations
97 A 6 13 19 0.584 0.427 View mutations
98 Q 11 8 19 0.440 0.437 View mutations
99 L 2 17 19 0.835 0.645 View mutations
100 Q 0 19 19 0.998 0.812 View mutations