P30281 (P30281)

Overview
Predicted structure (AF):
AF-P30281-F1-model_v4
Uniprot entry:
P30281
Gene:
P30281
Protein length:
292 residues
Mutations found:
5547
Benign based on D2Deep prediction:
3019 out of 5547 mutations
Pathogenic based on D2Deep prediction:
2528 out of 5547 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5547 mutations across 292 unique positions. There are 3019 benign and 2528 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 I 3 16 19 0.839 0.659 View mutations
127 Y 0 19 19 0.998 0.803 View mutations
128 T 0 19 19 0.987 0.879 View mutations
129 D 2 17 19 0.908 0.711 View mutations
130 H 0 19 19 0.965 0.701 View mutations
131 A 1 18 19 0.938 0.713 View mutations
132 V 1 18 19 0.945 0.674 View mutations
133 S 13 6 19 0.286 0.440 View mutations
134 P 12 7 19 0.382 0.412 View mutations
135 R 19 0 19 0.001 0.580 View mutations
136 Q 11 8 19 0.441 0.438 View mutations
137 L 1 18 19 0.953 0.606 View mutations
138 R 6 13 19 0.641 0.525 View mutations
139 D 15 4 19 0.254 0.476 View mutations
140 W 10 9 19 0.452 0.494 View mutations
141 E 0 19 19 0.999 0.834 View mutations
142 V 19 0 19 0.007 0.373 View mutations
143 L 19 0 19 0.000 0.409 View mutations
144 V 4 15 19 0.773 0.637 View mutations
145 L 18 1 19 0.056 0.161 View mutations
146 G 18 1 19 0.039 0.346 View mutations
147 K 13 6 19 0.330 0.443 View mutations
148 L 19 0 19 0.000 0.042 View mutations
149 K 13 6 19 0.310 0.401 View mutations
150 W 19 0 19 0.001 0.155 View mutations